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Understanding DEHP and Your Health - Cure Medical
DEHP (Di (2-ethylhexyl)phthalate) is listed as a known chemical to cause cancer and toxicity in males. This is especially important because the incidence of bladder cancer in people who have spinal cord injury (SCI) is 16 to 28 times higher than that in the general population. Source.
US California adds another Phthalate to the Proposition 65 .
dinp (di isononyl phthalate) was added to the list of chemicals known to the state of california to cause cancer last year. THE WARNING REQUIREMENT BECOMES EFFECTIVE A YEAR FROM THAT DATE, 20 DECEMBER 2014.
About DINP and California Proposition 65 | Medline .
CA Prop 65 - DINP The California Office of Environmental Health Hazard Assessment has added DINP to the Proposition 65 list of chemicals "known to the State of California to cause cancer." As stated above, the listing of a chemical does not necessarily mean a product containing the chemical is in "violation of any product-safety standards."
IRIS Bimonthly Public Meeting (Oct 2014) | Integrated Risk .
IRIS Bimonthly Public Meeting (Oct 2014) . There are no human epidemiological studies on DINP exposure and cancer. The human relevance of MNCLs observed in animals has been a topic of scientific debate. EPA is seeking public discussion of the human relevance of MNCL in rats and mice following exposure to DINP.
Diisononyl phthalate | C26H42O4 - PubChem
The pharmacokinetic and metabolic behaviour of (14)C-diisononyl phthalate (DINP CAS 68515-48-0, 97-98% pure) were investigated in male and Fischer 344 rats treated with a single oral dose of 50 or 500 mg/kg, and in male rats treated with five daily oral doses of 50, 150 and 500 mg/kg.
Diisononyl phthalate - Wikipedia
Diisononyl phthalate. DINP is listed as a substance "known to the State of California to cause cancer" under Proposition 65 legislation. Studies find that exposure to environmentally relevant concentrations of DINP in zebrafish disrupt the endocannabinoid system (ECS) and affect reproduction in …
FoodHandler Addresses California Prop 65
As the leader in food safety, FoodHandler is to complete a national change-over from DINP to Non-DINP Plasticizer. The state of California has included DINP as a cancer-causing carcinogen on the Proposition 65 list. By California Proposition 65 law, any items containing DINP chemical must either have the chemical replaced or have a Proposition 65.
Chemical enemy number one: how bad are phthalates really .
Feb 10, 2015· One of the first phthalates to raise a red flag, DEHP, was replaced in hundreds of consumer products with DiNP, only for researchers to discover a few years later that exposure to DiNP is correlated to male genital birth defects and impaired reproductive function in adult males.
Phthalates, Pesticides, and Bisphenol-A Exposure and the .
Phthalates with the highest production volume are diisononyl phthalate (DiNP), diisodecyl phthalate (DiDP), and di-2-ethyl-hexyl phthalate (DEHP) [2, 5]. Phthalates are used as plasticizers to increase stability and flexibility, to prevent brittleness, as a solvent for fragrances, and as inert ingredients.
American Chemistry Council Files Lawsuit to Remove DINP .
WASHINGTON (June 11, 2014) - The American Chemistry Council (ACC) Monday filed a lawsuit challenging the state of California's listing of diisononyl phthalate (DINP) under the Safe Drinking Water and Toxic Enforcement Act of 1986, also known as Proposition 65.
Toxicological Profile for DEHP - California
Cancer. According to U.S. EPA, there is sufficient evidence that DEHP causes cancer in laboratory animals. However, the International Agency for Research on Cancer considers the mechanism responsible for causing cancer in laboratory animals as unlikely to occur in humans; there are some who disagree with this finding. Neurological Effects.
Diisononyl Phthalate | OEHHA
Notice of a Public Hearing for a Safe Use Determination for Diisononyl Phthalate (DINP) in Vinyl Flooring Products; Chemical Listed Effective December 20, 2013 as Known to the State of California to Cause Cancer: Diisononyl Phthalate (DINP)
Diisononyl Phthalate (DINP)
Diisononyl Phthalate (DINP) Why am I being warned about potential exposure to DINP? ! DINP is on the Proposition 65 list because it can cause cancer. Exposure to DINP may increase the risk of cancer. Proposition 65 requires businesses to determine if they must provide a warning about exposures to listed chemicals. What is DINP?
DEHP - One of the Top 6 Chemical Threats to Humans
Jun 24, 2011· These chemicals have disrupted the endocrine systems of wildlife, causing testicular cancer, genital deformations, low sperm counts and infertility in a number of species, including polar bears, deer, whales and otters, just to name a few. Scientists believe phthalates are responsible for a similar pattern in humans as well.
Phthalates - Canadian Cancer Society
Phthalates. Another phthalate, diisononyl phthalate (DINP) has been linked to cancer in rats and mice. The California Office of Environmental Health Hazard Assessment includes DINP on their list of chemicals known to cause cancer. IARC and NTP have not classified DINP as a carcinogen.
DINP-DIDP: 5. What health effects can DIDP and DINP cause .
5. What health effects can DIDP and DINP cause in laboratory animals? If DIDP or DINP are swallowed, about 50% of it is absorbed from the gut into the blood. Absorption through the skin is very low in rats (about 4%) and even lower in humans.
Diisononyl Phthalate (DINP) - Proposition 65 Warnings Website
DINP is on the Proposition 65 list because it can cause cancer. Exposure to DINP may increase the risk of cancer. Proposition 65 requires businesses to determine if they must provide a warning about exposures to listed chemicals.
WARNING This product can expose you to chemicals including .
phthalate (DINP), which is known to the State of California to cause cancer & Di(2-ethylhexyl) phthalate (DEHP), which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to .P65Warnings WARNING
Chronic Hazard Advisory Panel Report on Diisononyl .
determine whether DINP in consumer products poses a chronic hazard and, if feasible, indicate the probable harm to human health resulting from exposures to DINP. This is the final report of that panel, the Chronic Hazard Advisory Panel (CHAP) on Diisononyl Phthalate (DINP). On any particular issue, a range of viewpoints was held among panel .
DINP and Prop 65 - Phthalates
To support the value chain, ACC's High Phthalates Panel and DINP manufacturers have calculated a level of exposure to DINP that is not expected to result in more than one excess case of cancer in 100,000 individuals exposed to the chemical over a 70-year lifetime, which is how an NSRL is defined in the OEHHA regulations.
Statement on DINP Webiste - sempermedusa
DINP to the California Office of Environmental Health Hazard Assessment Proposition 65 list. Q: What is Proposition 65? A: Enacted in 1986, Prop 65 is a California law intended to reduce or eliminate exposure to certain substances. It is comprised of a list of substances that the State of California recognizes as causing cancer and/or birth defects.
Biomonitoring Summary | CDC
DiNP administered to rodents produced liver and kidney toxicity, and may cause liver tumors by a mechanism involving peroxisomal proliferation. High dose DiNP was a developmental toxicant in rodents (NTP-CERHR, 2003c). Although DiNP is considered an animal carcinogen, neither IARC nor NTP has evaluated DiNP with respect to human carcinogenicity.
California Proposition 65 Reformulation of Phthalates in .
Jan 05, 2016· Diisononyl phthalate (DINP) and Di-n-hexyl phthalate (DnHP) These 6 phthalates are known to the State of California to cause cancer, birth defects, other reproductive harm or a combination of these toxicities.
Phthalates: Are They Safe? - WebMD
DINP causes tumors and developmental problems in lab rats. In 2014, California added it to its list of chemicals known to cause cancer. But it hasn't been proven to cause cancer in people.