benzyl alcohol toxicity

    BENZYL SALICYLATE || Skin Deep® Cosmetics Database | EWG

    Charles AK, Darbre PD. 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5): 422-34. EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

    Benzyl alcohol | Sigma-Aldrich

    Sigma-Aldrich offers a number of Benzyl alcohol products. View information & documentation regarding Benzyl alcohol, including CAS, MSDS & more.

    Opinion of the Scientific Committee on Food on Benzyl alcohol

    activity of benzyl alcohol at concentrations of 0.4-3.0 microl/ml (Montaguti et al., 1994). Subacute / subchronic toxicity Mice Benzyl alcohol was administered in corn oil to groups of 5 male and 5 B6C3F1 mice at doses of 0, 125, 250, 500, 1000, and 2000 mg/kg bw by gavage on five days a week for 12 doses over a 16-day period.

    Benzyl alcohol - Registration Dossier - ECHA

    Benzyl alcohol Benzyl alcohol (8CI) BENZYLALKOHOL Benzylic alcohol HYDROXYMETHYLBENZOL PHENYLCARBINOL PHENYLMETHANOL Phenylmethyl alcohol PHENYLMETHYLALKOHOL Sunmorl BK 20 Total tonnage band Total range: 10 000 - 100 000 tonnes per annum REACH Registered as: FULL Submitted: Joint Submission Publication dates First published: 03-Mar-2011 Last .

    BENZYL SALICYLATE || Skin Deep® Cosmetics Database | EWG

    About BENZYL SALICYLATE: Benzyl Salicylate is an ester of benzyl alcohol and salicylic acid; this ingredient has been associated with allergies and contact dermatitis. Function(s): Fragrance Ingredient; Ultraviolet Light Absorber; MASKING; UV ABSORBER.

    Material Safety Data Sheet Benzyl alcohol

    Benzyl alcohol contaminated with 1.4% hydrogen bromide and 1.2% of d issolved iron (II) polymerizes exothermally above 100 deg. C. Benzyl alcohol can extract and dissolve polystyrene plastic and may attack other plastics.

    Benzyl alcohol - Registration Dossier - ECHA

    Hazardous to the aquatic environment (acute / short-term) Reason for no classification: data lacking Hazardous to the aquatic environment (long-term)

    Provisional Peer-Reviewed Toxicity Values for Benzyl .

    Benzyl alcohol is also used as a preservative in medicinal products and was identified as a component associated with brain hemorrhage in infants and neonates (NTP, 1989a). Literature searches were conducted from 1960s through May 28, 2009 for studies relevant to the derivation of provisional toxicity values for benzyl alcohol. Databases searched

    Benzyl Alcohol: Toxic Agent in Neonatal Units

    haps unmetabolized benzyl alcohol) with resulting metabolic acidosis and toxicity. Known toxic effects on benzyl alcohol include respiratory failure, vaso-dilation, hypotension, convulsions, and paralysis; little is known specifically about toxicity of the compound in newborn infants. Most studies of ben-zyl alcohol toxicity in animals5 have .

    Ulesfia (Benzyl Alcohol Lotion for Topical Use): Side .

    Although expected systemic exposure of benzyl alcohol from proper use of ULESFIA® Lotion is substantially lower than those reported in association with the gasping syndrome, the minimum amount of benzyl alcohol at which toxicity may occur is not known. Geriatric Use

    Final report on the safety assessment of Benzyl Alcohol .

    Author information: (1)Cosmetic Ingredient Review Expert Panel, Washington, DC 20036, USA. Benzyl Alcohol is an aromatic alcohol used in a wide variety of cosmetic formulations as a fragrance component, preservative, solvent, and viscosity-decreasing agent. Benzoic Acid is an aromatic acid used in a .

    Benzyl alcohol - Wikipedia

    Neonatal Deaths Associated With Use Of Benzyl Alcohol -- United States . Sixteen neonatal deaths thought to be caused by the benzyl alcohol preservative used in some intravascular solutions have been reported to the Food and Drug Administration (FDA) by 2 medical centers (1,2).

    Benzyl Alcohol – toxicity, side effects, diseases and .

    Jul 05, 2018· Benzyl alcohol may cause many different side effects, usually in solutions higher than five percent. Avoid using products that contain benzyl alcohol, especially the ones that have more than five percent solutions. In case of benzyl alcohol poisoning or exposure, follow the necessary first aid procedures as specified below.

    Benzyl alcohol | C6H5CH2OH - PubChem

    Benzyl alcohol | C6H5CH2OH or C7H8O | CID 244 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological .

    Material Safety Data Sheet - Fisher Scientific

    If released to water, benzyl alcohol is expected to undergo microbial degradation under aerobic and anaerobic conditions. Physical: In the atmosphere, benzyl alcohol is expected to exist almost entirely in the vapor phase. The estimated half-life for the vapor phase reaction of benzyl alcohol with photochemically produced hydroxyl radicals is 2 .

    Benzyl Alcohol (Inactive Ingredient) - Drugs

    Aug 30, 2018· Benzyl alcohol is also used as a common preservative in many injectable drugs. Benzyl alcohol and benzoic acid have been associated in the past with toxicity and death in neonates who received injectable flush or lavage salines solutions containing benzyl alcohol. Neonates, especially if ill, may not be able to adequately metabolize benzyl alcohol.

    Evaluation of propofol containing 2% benzyl alcohol .

    Propofol emulsion containing benzyl alcohol preservative (BA) was evaluated in cats. Eight (PB) received 1% propofol containing 2% benzyl alcohol and eight (PC) preservative-free propofol. In phase 1, cats were anaesthetised (8 mg/kg) three times at …

    How toxic is benzyl alcohol? - Quora

    Jan 22, 2016· Its toxic effects are nearly the same as toulene, but at much smaller doses. In non-lethal doses it leads to symptoms of drunkenness and alcohol poisoning; it doesn't appear to have any long-term effects with a single acute dose, but long term dosing causes irreversible muscle tremors.

    benzyl alcohol toxicity,

    Benzyl Alcohol Toxicity - Medlab Gear

    Benzyl alcohol is an organic, aromatic alcohol with a color that is water-white with a sharp burning taste and a low aromatic odor. Benzyl alcohol can be found naturally as being produced by a variety of plants and is used in essential oils, fruits and in teas.

    Benzyl alcohol, cinnamate | C16H14O2 - PubChem

    Benzyl cinnamate is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and 2) they consist of one or more of .

    Benzyl Alcohol – toxicity, side effects, diseases and .

    Jul 05, 2018· Benzyl alcohol may be toxic by ingestion. Common side effects of benzyl alcohol lotion (five percent) include irritations of the skin, scalp, eyes and numbness at the site of the application. Other negative side effects include rashes, hives, shortness of breath, wheezing, cough, swelling of the lips, tongue and throat.

    Provisional Peer-Reviewed Toxicity Values for Benzyl .

    Committee derived an ADI of 0–5 mg/kg for benzyl alcohol (WHO, 2005). The National Toxicology Program (NTP, 1989a) has conducted 16-day and 13-week oral studies and a 2-year oral exposure cancer bioassay of benzyl alcohol. Neither CalEPA (2008a,b) nor ATSDR (2008) has assessed the toxicity of benzyl alcohol.

    benzyl alcohol toxicity,

    Benzyl Alcohol: Toxic Agent in Neonatal Units

    haps unmetabolized benzyl alcohol) with resulting metabolic acidosis and toxicity. Known toxic effects on benzyl alcohol include respiratory failure, vaso-dilation, hypotension, convulsions, and paralysis; little is known specifically about toxicity of the compound in newborn infants. Most studies of ben-zyl alcohol toxicity in animals5 have .

    Benzyl alcohol - Wikipedia

    Benzyl alcohol is an aromatic alcohol with the formula C 6 H 5 CH 2 OH. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH.Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure.

    Benzyl chloride - US EPA

    Benzyl chloride can be used in the manufacture of synthetic tannins and as a gum inhibitor in petrol. (1) Benzyl chloride has been used as an irritant gas in chemical warfare. (1) Sources and Potential Exposure Sources of benzyl chloride emissions into the air include emissions or venting with other gases in industrial settings.

    Ingredient Watch List: Benzyl Alcohol, Another Irritating .

    Jan 02, 2013· Hans, the benzyl alcohol in your eye drops is probably there as a preservative, and is probably there in concentrations low enough not to cause you any problems. However, having said that, benzyl alcohol is known specifically to be a severe eye irritant, and at certain concentrations it can even cause necrosis (the death of eye tissue).

    Safety Data Sheet - Fisher Scientific

    Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 01.19.2015 Page 2 of 7 Benzyl Alcohol Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - .gsmsds Avoid release to the environment Wear protective gloves/protective clothing/eye …

    Benzyl Alcohol (Inactive Ingredient) - Drugs

    Benzyl alcohol is also used as a common preservative in many injectable drugs. Benzyl alcohol and benzoic acid have been associated in the past with toxicity and death in neonates who received injectable flush or lavage salines solutions containing benzyl alcohol. Neonates, especially if ill, may not be able to adequately metabolize.

    Talk:Benzyl alcohol - Wikipedia

    Any discussion of benzyl alcohol toxicity needs to take dose into account. Low doses have little or no toxicity. It gets metabolized. High doses can be very toxic. This is no different from ethyl alcohol. Almost all Americans have had benzyl alcohol administered since it is a …

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